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The Bible repeatedly mentions the bitterness of soul (1 Samuel 1:10; Job 3:20; Job 7:11; Job 10:1; Job 21:25; Isaiah 38:15). Job testified to speaking in the bitterness of his soul—weary of his life (Job 10:1). Hannah “was in bitterness of soul” (1 Samuel 1:10) when she spoke to the Lord concerning her desire to birth a son. Interestingly, the Book of Job contains the majority of references to bitterness of soul. It is hard to imagine any mortal man enduring more afflictions of the soul than Job. He was afflicted so deeply, he cursed the day that he was born (Job 3:1). Eventually, his bitterness of soul won out and caused him to sin against the Lord. Hannah, however, spoke to the Lord in bitterness of soul and God rewarded her for her faithfulness.
A good Bible student often incorporates many of the same tactics as a good detective. Defining Bible words involves such a task. No single verse specifically defines the word bitterness. Yet, a careful study of a few verses will help to bring the pieces together and to provide understanding. According to Isaiah, bitterness and peace are at opposite ends of the emotional spectrum (Isaiah 38:17). Proverbs associates the word bitter directly to the word sharp (Proverbs 5:4). And, lastly, the word bitter is connected to the word affliction (2 Kings 14:26, Lamentations 1:4). Using these scriptural clues, a good student will understand bitterness to be a sharp affliction. Additionally, consider the connection between the words bitter and bite, making bitterness a sharp affliction with bite. Bitterness always begins on the inside of an individual and, as we will learn, eventually works its way to the outside for others to see.
Humility moves God to action. This common theme runs throughout the Bible; however, our passage reveals some truth otherwise hidden. According to Second Chronicles, the people of God are responsible to humble themselves. While doing so, they must also pray, seek God’s face, and turn from their wicked ways. God’s use of the word then in the passage reveals that God’s actions result from the actions of His people. Their humility will move the Lord to action. If, or when, they humble themselves, God hears from heaven, forgives their sin, and heals their land. God takes note when people display humility (Isaiah 57:15; Isaiah 66:1-2). Though some things have changed concerning Israel versus the church, God remains constant and is still looking for humility in the lives of His children.
Our previous studies have discussed the Bible's built-in dictionary. Interestingly, the discovery of this method of defining words is not new. In fact, men like King James VI (also known as King James I) commented on God's graciousness concerning His word. He pointed out that the definitions of many Bible words could be found by considering surrounding words. John Eadie explains this in his book:  The English Bible, vol. 2, London, Macmillan, 1876, p. 191. Our study in humility is a case in point. The true riches of this word can only be gleaned when one considers some of the words used in close proximity of the word humble (along with its variations). These words include: croucheth (Psalm 10:10), lowly (Proverbs 16:19), boweth down (Isaiah 2:9), bowed down (Isaiah 2:11), brought down (Isaiah 5:15), hewn down (Isaiah 10:33), and abased (Luke 14:11; Luke 18:14). God wants the Bible student to understand the depths and riches of His word and words. In this case, He clearly indicated that humility results from one being brought low.