God directs believers to submit to various authorities; yet, above all these authorities, we must submit ourselves unto God. This submission entails submitting our whole being (body, soul, and spirit) to God. Christ purchased us with His own blood on Calvary (1 Corinthians 6:20), and we are no longer our own. This means that God has the authority to tell us what to eat, where to go, what to watch, what to listen to, what to read, where to attend church, how to worship Him, and the list continues without end. Every aspect of our lives, from our thought life to our every action, remains God’s business. We should wisely submit every aspect of our lives to Him. Submitting to God enables us to resist the Devil and when we resist him, the Devil flees.
The passage may appear to directly equate obedience and submission together, but each word conveys a separate and distinct concept. Although today's passage includes both obedience and submission, it is important to recognize that these two words involve separate acts. Earlier studies noted a twofold definition of obedience: first, having an attentive ear, followed by acting upon what has been said. Dividing submission into two parts helps to better understand it too (sub + mission). The prefix sub means under (thus a submarine travels under the water), and the root word mission means to be sent out. Obedience, therefore, emphasizes the act of hearing and doing, while submission emphasizes the act of placing oneself under the authority of another.
This passage provides some of the last recorded words from Paul to Timothy. In it, Paul charged Timothy to “preach the word” (2 Timothy 4:2), “watch thou in all things, endure afflictions,” and “make full proof” of his ministry (2 Timothy 4:5). Paul then focused Timothy’s attention toward Paul’s departure from this world. The three statements in 2 Timothy 4:7 point to Paul’s life of diligence. Paul had fought the fight, finished his course, and kept the faith. He certainly could be viewed by none as a lazy man. In fact, Paul was far from slothful, warning others day and night (Acts 20:31). Before salvation, Paul worked hard to destroy Christians and Christianity. After he learned the truth, he determined to give his best to the Lord and His work.